STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)    
Predicted Functional Partners:
Rvan_1831
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: rpt:Rpal_2647 methylcitrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.954
Rvan_3206
KEGG: bov:BOV_1106 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.954
Rvan_1914
TIGRFAM: malate synthase A; KEGG: pzu:PHZ_c3212 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
   
 0.953
Rvan_0023
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: azl:AZL_023130 acetyl-CoA C-acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
Rvan_0557
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: rce:RC1_1744 3-ketoacyl-CoA thiolase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
Rvan_0850
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: maq:Maqu_2016 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
Rvan_3408
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: tmz:Tmz1t_0732 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
Rvan_1827
PFAM: Aldehyde Dehydrogenase; KEGG: rru:Rru_A0931 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.930
Rvan_2307
PFAM: Aldehyde Dehydrogenase; KEGG: avi:Avi_5719 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.930
Rvan_3411
KEGG: rsp:RSP_2962 methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
   
 0.930
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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