STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_1731Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (458 aa)    
Predicted Functional Partners:
gshB
TIGRFAM: glutathione synthetase; KEGG: mlo:mll4735 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; Belongs to the prokaryotic GSH synthase family.
    
 0.921
Rvan_2611
PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: bbt:BBta_7039 leucine aminopeptidase; Belongs to the peptidase M17 family.
  
  
  0.911
Rvan_0133
KEGG: tmz:Tmz1t_0521 allophanate hydrolase subunit 1; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1.
     
  0.900
Rvan_0134
TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: met:M446_2133 UreA amidolyase related protein; SMART: Allophanate hydrolase subunit 2.
     
  0.900
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
Rvan_0954
KEGG: aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase.
     
  0.900
Rvan_2422
TIGRFAM: gamma-glutamyltransferase; KEGG: pde:Pden_0660 gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
     
  0.900
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
Rvan_1188
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.811
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.