Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_1822TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone repeat-containing protein; KEGG: azo:azo2972 ExaA2 protein; SMART: Pyrrolo-quinoline quinone beta-propeller repeat. (623 aa)    
Predicted Functional Partners:
Rvan_1825
PFAM: cytochrome c class I; KEGG: azl:AZL_a09940 cytochrome c550.
 
 
 0.928
Rvan_1824
Hypothetical protein; KEGG: azo:azo2974 putative cytochrome c550.
 
 
 0.925
pqqB
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.839
pqqC
Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.824
Rvan_1823
PFAM: pentapeptide repeat protein; KEGG: azo:azo2973 pentapeptide repeat-containing protein.
 
  
 0.786
pqqE
Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.770
Rvan_0685
KEGG: rpb:RPB_3420 coenzyme PQQ synthesis D.
 
  
 0.581
Rvan_2235
KEGG: sus:Acid_5771 hypothetical protein.
 
 
 0.504
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
      
 0.447
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
      
 0.441
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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