STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_1827PFAM: Aldehyde Dehydrogenase; KEGG: rru:Rru_A0931 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
Rvan_1029
PFAM: iron-containing alcohol dehydrogenase; KEGG: rpa:RPA1205 putative alcohol dehydrogenase.
 
 0.953
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.930
Rvan_3597
acetate/CoA ligase; KEGG: rsq:Rsph17025_0782 acetate--CoA ligase; TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase.
   
 0.930
Rvan_0682
KEGG: hne:HNE_0560 S-(hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase, class III; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.925
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.924
Rvan_1054
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bid:Bind_1770 alcohol dehydrogenase.
  
 
 0.910
Rvan_1055
PFAM: Alcohol dehydrogenase GroES domain protein; Twin-arginine translocation pathway, signal sequence, subgroup; Alcohol dehydrogenase zinc-binding domain protein; KEGG: ank:AnaeK_3351 alcohol dehydrogenase GroES domain protein.
  
 
 0.910
Rvan_1592
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: msl:Msil_0202 alcohol dehydrogenase zinc-binding domain protein.
  
 
 0.910
Rvan_0941
PFAM: acetyl-CoA hydrolase/transferase; manually curated; KEGG: rpd:RPD_0322 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase.
  
 
 0.908
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.901
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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