STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_2164KEGG: bra:BRADO2682 methylmalonyl-CoA mutase small subunit (MCM-beta); PFAM: methylmalonyl-CoA mutase. (661 aa)    
Predicted Functional Partners:
Rvan_2165
TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: azc:AZC_1772 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
 
0.993
Rvan_3650
TIGRFAM: methylmalonyl-CoA epimerase; KEGG: xau:Xaut_4617 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.973
Rvan_1142
TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: azc:AZC_0992 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
 
 
 0.950
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.909
sucD-2
CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.909
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.908
Rvan_3430
Succinate--CoA ligase (ADP-forming); KEGG: oca:OCAR_6737 succinyl-CoA synthetase beta chain (SCS-alpha); PFAM: ATP-grasp domain protein; ATP-citrate lyase/succinyl-CoA ligase.
  
 
 0.908
Rvan_0326
PFAM: AMP-dependent synthetase and ligase; KEGG: azc:AZC_3298 malonyl-CoA synthase.
     
 0.901
Rvan_2273
KEGG: mno:Mnod_1086 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein.
 
  
 0.845
Rvan_0374
PFAM: ArgK protein; KEGG: mag:amb1534 periplasmic protein kinase ArgK.
 
  
 0.836
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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