| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rvan_0098 | Rvan_1366 | Rvan_0098 | Rvan_1366 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rpe:RPE_0925 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.920 |
| Rvan_0098 | Rvan_2000 | Rvan_0098 | Rvan_2000 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rpe:RPE_0925 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PFAM: phosphatidate cytidylyltransferase; KEGG: rlg:Rleg_1781 phosphatidate cytidylyltransferase. | 0.954 |
| Rvan_0098 | Rvan_2387 | Rvan_0098 | Rvan_2387 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rpe:RPE_0925 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: rpt:Rpal_2218 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.951 |
| Rvan_0098 | psd | Rvan_0098 | Rvan_2388 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rpe:RPE_0925 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.559 |
| Rvan_0867 | Rvan_2280 | Rvan_0867 | Rvan_2280 | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.913 |
| Rvan_0867 | Rvan_2387 | Rvan_0867 | Rvan_2387 | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | KEGG: rpt:Rpal_2218 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| Rvan_0867 | glyA | Rvan_0867 | Rvan_0739 | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.940 |
| Rvan_0867 | trpA | Rvan_0867 | Rvan_0906 | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.924 |
| Rvan_0867 | trpB | Rvan_0867 | Rvan_0907 | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.933 |
| Rvan_0867 | trpB-2 | Rvan_0867 | Rvan_1701 | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.905 |
| Rvan_1366 | Rvan_0098 | Rvan_1366 | Rvan_0098 | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rpe:RPE_0925 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.920 |
| Rvan_1366 | Rvan_2000 | Rvan_1366 | Rvan_2000 | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PFAM: phosphatidate cytidylyltransferase; KEGG: rlg:Rleg_1781 phosphatidate cytidylyltransferase. | 0.918 |
| Rvan_1366 | Rvan_2387 | Rvan_1366 | Rvan_2387 | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: rpt:Rpal_2218 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.917 |
| Rvan_2000 | Rvan_0098 | Rvan_2000 | Rvan_0098 | PFAM: phosphatidate cytidylyltransferase; KEGG: rlg:Rleg_1781 phosphatidate cytidylyltransferase. | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rpe:RPE_0925 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.954 |
| Rvan_2000 | Rvan_1366 | Rvan_2000 | Rvan_1366 | PFAM: phosphatidate cytidylyltransferase; KEGG: rlg:Rleg_1781 phosphatidate cytidylyltransferase. | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.918 |
| Rvan_2000 | Rvan_2387 | Rvan_2000 | Rvan_2387 | PFAM: phosphatidate cytidylyltransferase; KEGG: rlg:Rleg_1781 phosphatidate cytidylyltransferase. | KEGG: rpt:Rpal_2218 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.921 |
| Rvan_2000 | psd | Rvan_2000 | Rvan_2388 | PFAM: phosphatidate cytidylyltransferase; KEGG: rlg:Rleg_1781 phosphatidate cytidylyltransferase. | Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.497 |
| Rvan_2280 | Rvan_0867 | Rvan_2280 | Rvan_0867 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase. | KEGG: rce:RC1_3167 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | 0.913 |
| Rvan_2280 | Rvan_2387 | Rvan_2280 | Rvan_2387 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase. | KEGG: rpt:Rpal_2218 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.905 |
| Rvan_2280 | glyA | Rvan_2280 | Rvan_0739 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |