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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
Rvan_2417PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: amc:MADE_00668 DNA ligase. (527 aa)    
Predicted Functional Partners:
Rvan_2096
KEGG: amc:MADE_00669 RNA procession exonuclease-like protein.
 
 0.988
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.925
Rvan_0003
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.908
Rvan_2098
DEAD/H associated domain protein; KEGG: amc:MADE_00670 ATP-dependent RNA helicase, DEAD/DEAH box family protein; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
 
    0.844
Rvan_0540
Hypothetical protein; Manually curated; KEGG: oan:Oant_4041 hypothetical protein.
 
     0.792
Rvan_0173
KEGG: bja:blr1149 hypothetical protein.
 
     0.786
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.612
Rvan_2420
Hypothetical protein; KEGG: pzu:PHZ_c3267 nucleotidyltransferase/DNA polymerase involved in DNA repair.
 
 
 0.606
Rvan_2418
PFAM: protein of unknown function DUF1491; KEGG: oca:OCAR_6628 hypothetical protein.
       0.453
Rvan_0266
KEGG: exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.444
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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