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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (449 aa)    
Predicted Functional Partners:
Rvan_0258
PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: mlo:mlr5329 malic enzyme.
  
  
 0.914
Rvan_1566
PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: rce:RC1_0405 malic enzyme.
  
  
 0.914
Rvan_0121
PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_0943 putative propionate--CoA ligase.
     
 0.912
Rvan_0941
PFAM: acetyl-CoA hydrolase/transferase; manually curated; KEGG: rpd:RPD_0322 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase.
     
 0.912
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.912
Rvan_2703
PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; KEGG: pzu:PHZ_p0184 phosphoketolase.
 
  
 0.911
Rvan_1827
PFAM: Aldehyde Dehydrogenase; KEGG: rru:Rru_A0931 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.909
Rvan_3597
acetate/CoA ligase; KEGG: rsq:Rsph17025_0782 acetate--CoA ligase; TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase.
     
 0.908
Rvan_1914
TIGRFAM: malate synthase A; KEGG: pzu:PHZ_c3212 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
   
  
 0.813
Rvan_1333
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
  
 0.721
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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