Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_3015KEGG: oca:OCAR_6668 hopanoid biosynthesis associated radical SAM protein HpnH; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM domain protein. (380 aa)    
Predicted Functional Partners:
Rvan_3017
TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; KEGG: bph:Bphy_4137 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase.
   
 0.951
Rvan_2491
TIGRFAM: hopanoid biosynthesis associated RND transporter like protein HpnN; KEGG: bbt:BBta_2973 putative protein export membrane protein.
 
   
 0.855
Rvan_3021
KEGG: cyn:Cyan7425_4598 hopene-associated glycosyltransferase HpnB; TIGRFAM: hopene-associated glycosyltransferase HpnB; PFAM: glycosyl transferase family 2.
 
   
 0.791
Rvan_3016
Hopanoid-associated phosphorylase; KEGG: cti:RALTA_B1984 hypothetical protein; TIGRFAM: hopanoid-associated phosphorylase; PFAM: purine or other phosphorylase family 1.
  
     0.775
Rvan_3018
KEGG: rpc:RPC_1719 amine oxidase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase.
 
    0.739
Rvan_3020
KEGG: oca:OCAR_6674 squalene synthase HpnC; TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase.
 
   
 0.614
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.605
Rvan_3019
TIGRFAM: squalene synthase HpnD; KEGG: msl:Msil_3241 squalene synthase HpnD; PFAM: Squalene/phytoene synthase.
 
   
 0.579
pqqC
Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.538
pqqB
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.513
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (14%) [HD]