Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_3133PFAM: Na+/solute symporter; KEGG: tgr:Tgr7_1022 SSF family Na(+)/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (620 aa)    
Predicted Functional Partners:
Rvan_3134
TIGRFAM: putative solute symporter protein; KEGG: bgl:bglu_1g25350 membrane protein-like protein.
  
    0.834
Rvan_3305
PFAM: AMP-dependent synthetase and ligase; KEGG: pla:Plav_3087 AMP-dependent synthetase and ligase.
 
  
 0.558
Rvan_3135
Two component transcriptional regulator, LuxR family; KEGG: bja:blr1194 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver.
  
  
 0.536
Rvan_0044
KEGG: hoh:Hoch_6534 benzoate-CoA ligase family; TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase.
  
  
 0.453
Rvan_0111
acetoacetyl-CoA synthase; KEGG: bmr:BMI_I21 acetyl-coenzyme A synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase.
  
  
 0.453
Rvan_0121
PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_0943 putative propionate--CoA ligase.
  
  
 0.453
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.453
Rvan_3597
acetate/CoA ligase; KEGG: rsq:Rsph17025_0782 acetate--CoA ligase; TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase.
  
  
 0.453
Rvan_1914
TIGRFAM: malate synthase A; KEGG: pzu:PHZ_c3212 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
  
  
 0.451
Rvan_3132
KEGG: pla:Plav_0503 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family.
       0.447
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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