STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_3140PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: azl:AZL_013840 DNA-invertase. (193 aa)    
Predicted Functional Partners:
Rvan_3141
PFAM: EcoEI R domain protein; type III restriction protein res subunit; protein of unknown function DUF450; KEGG: hsdR3; type I restriction-modification system RcaSBIV subunit R; SMART: DEAD-like helicase.
     
 0.500
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
    0.473
Rvan_3142
PFAM: restriction modification system DNA specificity domain; KEGG: ava:Ava_3267 restriction modification system DNA specificity subunit.
  
  
 0.465
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.446
Rvan_3143
PFAM: N-6 DNA methylase; KEGG: hsdM3; type I restriction-modification system RcaSBIV subunit M.
     
 0.440
Rvan_1051
PFAM: protein of unknown function DUF927; KEGG: esa:ESA_03018 hypothetical protein.
     
 0.417
Rvan_2789
PFAM: protein of unknown function DUF927; KEGG: zinc-binding domain of primase-helicase family protein.
     
 0.417
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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