Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_3142PFAM: restriction modification system DNA specificity domain; KEGG: ava:Ava_3267 restriction modification system DNA specificity subunit. (367 aa)    
Predicted Functional Partners:
Rvan_3143
PFAM: N-6 DNA methylase; KEGG: hsdM3; type I restriction-modification system RcaSBIV subunit M.
 
 0.990
Rvan_3141
PFAM: EcoEI R domain protein; type III restriction protein res subunit; protein of unknown function DUF450; KEGG: hsdR3; type I restriction-modification system RcaSBIV subunit R; SMART: DEAD-like helicase.
 
 
 0.975
Rvan_1907
PFAM: N-6 DNA methylase; KEGG: sme:SMc02296 putative modification enzyme transmembrane protein.
 
 
 0.905
Rvan_2836
KEGG: bid:Bind_2672 N-6 DNA methylase; TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase.
 
 
 0.888
Rvan_1419
PFAM: N-6 DNA methylase; KEGG: rme:Rmet_6243 hypothetical protein.
  
 
 0.808
Rvan_2833
Restriction modification system DNA specificity domain protein; KEGG: ana:all2687 type I restriction-modification enzyme S subunit; manually curated; PFAM: restriction modification system DNA specificity domain.
   
 0.739
Rvan_1905
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.708
Rvan_2832
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.685
Rvan_1474
KEGG: syf:Synpcc7942_0725 DEAD/DEAH box helicase-like; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase.
 
  
 0.580
Rvan_3140
PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: azl:AZL_013840 DNA-invertase.
     
 0.469
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.