Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_3344Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)    
Predicted Functional Partners:
Rvan_3631
TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; KEGG: rpa:RPA0535 ATP-dependent helicase HrpB; SMART: helicase domain protein; DEAD-like helicase.
   
 0.873
Rvan_1483
KEGG: sfu:Sfum_3853 hypothetical protein.
  
 0.872
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.833
Rvan_0447
KEGG: rpe:RPE_1474 hypothetical protein.
   
  0.810
Rvan_2855
Hypothetical protein; KEGG: ana:all0192 serine/threonine kinase.
   
 0.803
Rvan_1975
PFAM: histone deacetylase superfamily; KEGG: histone deacetylase.
   
 0.793
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.788
Rvan_2019
KEGG: helicase domain protein; PFAM: helicase domain protein; SMART: helicase domain protein.
    
 0.781
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.781
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
 
 0.779
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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