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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Rvan_3411KEGG: rsp:RSP_2962 methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase. (496 aa)    
Predicted Functional Partners:
Rvan_3414
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; KEGG: rle:pRL110406 putative 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family.
 
 0.968
Rvan_3409
PFAM: acyl-CoA dehydrogenase domain-containing protein; KEGG: azo:azo0394 acyl-CoA dehydrogenase.
  
 
  0.959
Rvan_0900
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pla:Plav_2894 6-phosphogluconate dehydrogenase NAD-binding.
 
 
 0.936
Rvan_1831
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: rpt:Rpal_2647 methylcitrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.933
Rvan_3098
PFAM: aminotransferase class-III; KEGG: mno:Mnod_3410 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.931
Rvan_1148
PFAM: carboxyl transferase; KEGG: carboxyl transferase.
   
 
 0.924
Rvan_2264
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pnu:Pnuc_1611 methylmalonyl-CoA decarboxylase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.924
Rvan_3408
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: tmz:Tmz1t_0732 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.919
Rvan_0121
PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_0943 putative propionate--CoA ligase.
   
 0.914
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.914
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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