Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_3429PFAM: Aldehyde Dehydrogenase; KEGG: oca:OCAR_6738 succinate-semialdehyde dehydrogenase. (471 aa)    
Predicted Functional Partners:
Rvan_1029
PFAM: iron-containing alcohol dehydrogenase; KEGG: rpa:RPA1205 putative alcohol dehydrogenase.
 
 0.972
Rvan_3430
Succinate--CoA ligase (ADP-forming); KEGG: oca:OCAR_6737 succinyl-CoA synthetase beta chain (SCS-alpha); PFAM: ATP-grasp domain protein; ATP-citrate lyase/succinyl-CoA ligase.
  
 0.841
sucD-2
CoA-binding domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.803
Rvan_3602
TIGRFAM: glycyl-radical enzyme activating protein family; KEGG: dvu:DVU2271 pyruvate formate-lyase activating enzyme, putative; PFAM: Radical SAM domain protein.
 
  
 0.714
Rvan_1333
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.690
Rvan_3601
PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; KEGG: dvu:DVU2272 formate acetyltransferase, putative.
 
  
 0.682
Rvan_1644
KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein.
  
  
 0.541
Rvan_0558
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: rce:RC1_1743 fatty acid oxidation complex alpha subunit.
  
 0.539
Rvan_0849
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: dar:Daro_1547 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.539
Rvan_2899
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: rce:RC1_0547 peroxisomal bifunctional enzyme.
  
 0.539
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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