Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_3479KEGG: azc:AZC_2924 sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase. (651 aa)    
Predicted Functional Partners:
Rvan_1285
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.808
Rvan_3478
KEGG: mch:Mchl_5523 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein.
 
     0.701
Rvan_3477
PFAM: Hydantoinase B/oxoprolinase; KEGG: mch:Mchl_5522 hydantoinase B/oxoprolinase.
 
     0.676
Rvan_3476
PFAM: Acetone carboxylase gamma subunit; KEGG: azc:AZC_2921 acetone carboxylase gamma subunit.
 
     0.653
Rvan_1333
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
  
 0.554
Rvan_2075
KEGG: xau:Xaut_1211 aliphatic sulfonate ABC transporter periplasmic ligand-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; SMART: extracellular solute-binding protein family 3.
 
      0.529
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (32%) [HD]