SEE97394.1 protein (Haloactinobacterium album)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

SEE97394.1

Carbohydrate ABC transporter substrate-binding protein, CUT1 family. (432 aa)

Predicted Functional Partners:

SEE97384.1

0.900

SEE97374.1

0.868

SEE97639.1

0.829

SEE97629.1

0.822

SED53159.1

0.762

SED76102.1

0.732

SEE65602.1

0.699

SEE28160.1

0.669

SED91770.1

0.668

SEE97660.1

0.667

Your Current Organism:

Haloactinobacterium album

NCBI taxonomy Id: 648782
Other names: Bogoriellaceae bacterium YIM 93306, CCTCC AB 208069, DSM 21368, H. album, Haloactinobacterium album Tang et al. 2010, KCTC 19413, YIM 93306

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SED53159.1	SEE28160.1	SAMN04488554_0090	SAMN04488554_1980	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	Multiple sugar transport system substrate-binding protein.	0.758
SED53159.1	SEE65602.1	SAMN04488554_0090	SAMN04488554_2331	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	ABC-type glycerol-3-phosphate transport system, substrate-binding protein.	0.756
SED53159.1	SEE97384.1	SAMN04488554_0090	SAMN04488554_4016	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	Multiple sugar transport system permease protein.	0.590
SED53159.1	SEE97394.1	SAMN04488554_0090	SAMN04488554_4017	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.762
SED53159.1	SEE97639.1	SAMN04488554_0090	SAMN04488554_4041	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	Carbohydrate ABC transporter membrane protein 1, CUT1 family.	0.590
SED76102.1	SEE97394.1	SAMN04488554_0626	SAMN04488554_4017	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.732
SED91770.1	SEE65602.1	SAMN04488554_1056	SAMN04488554_2331	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	ABC-type glycerol-3-phosphate transport system, substrate-binding protein.	0.703
SED91770.1	SEE97394.1	SAMN04488554_1056	SAMN04488554_4017	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.668
SEE28160.1	SED53159.1	SAMN04488554_1980	SAMN04488554_0090	Multiple sugar transport system substrate-binding protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.758
SEE28160.1	SEE97394.1	SAMN04488554_1980	SAMN04488554_4017	Multiple sugar transport system substrate-binding protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.669
SEE65602.1	SED53159.1	SAMN04488554_2331	SAMN04488554_0090	ABC-type glycerol-3-phosphate transport system, substrate-binding protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.756
SEE65602.1	SED91770.1	SAMN04488554_2331	SAMN04488554_1056	ABC-type glycerol-3-phosphate transport system, substrate-binding protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.703
SEE65602.1	SEE97394.1	SAMN04488554_2331	SAMN04488554_4017	ABC-type glycerol-3-phosphate transport system, substrate-binding protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.699
SEE97374.1	SEE97384.1	SAMN04488554_4015	SAMN04488554_4016	Multiple sugar transport system permease protein.	Multiple sugar transport system permease protein.	0.949
SEE97374.1	SEE97394.1	SAMN04488554_4015	SAMN04488554_4017	Multiple sugar transport system permease protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.868
SEE97374.1	SEE97639.1	SAMN04488554_4015	SAMN04488554_4041	Multiple sugar transport system permease protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family.	0.738
SEE97384.1	SED53159.1	SAMN04488554_4016	SAMN04488554_0090	Multiple sugar transport system permease protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.590
SEE97384.1	SEE97374.1	SAMN04488554_4016	SAMN04488554_4015	Multiple sugar transport system permease protein.	Multiple sugar transport system permease protein.	0.949
SEE97384.1	SEE97394.1	SAMN04488554_4016	SAMN04488554_4017	Multiple sugar transport system permease protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.900
SEE97384.1	SEE97629.1	SAMN04488554_4016	SAMN04488554_4040	Multiple sugar transport system permease protein.	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	0.825

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.706

expected number of edges:

14

PPI enrichment p-value:

3.36e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

8 of 114

1.41

2.12

5.02e-08

GO:0010467

Gene expression

10 of 236

1.19

1.68

7.21e-09

GO:0009059

Macromolecule biosynthetic process

9 of 243

1.14

1.45

1.21e-07

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 362

0.96

1.04

2.60e-06

GO:0034641

Cellular nitrogen compound metabolic process

10 of 700

0.72

0.66

2.91e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 61

1.63

2.59

5.54e-08

GO:0019843

rRNA binding

5 of 43

1.63

1.94

1.80e-05

GO:0003676

Nucleic acid binding

7 of 572

0.65

0.4

0.0298

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

8 of 65

1.66

3.21

1.54e-10

GO:0015934

Large ribosomal subunit

3 of 9

2.09

2.08

7.14e-05

GO:0032991

Protein-containing complex

4 of 176

0.92

0.61

0.0128

GO:0005622

Intracellular anatomical structure

11 of 1309

0.49

0.43

7.81e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:106

Ribosome, and Translational elongation

10 of 79

1.67

3.81

7.68e-14

CL:90

Translation, and Transcription, DNA-templated

11 of 128

1.5

3.13

4.73e-14

CL:118

Ribosome

7 of 57

1.66

2.9

4.61e-09

CL:119

Structural constituent of ribosome

6 of 52

1.63

2.48

1.78e-07

CL:164

rRNA-binding, and Elongation factor Tu domain 2

4 of 19

1.89

2.25

1.39e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

8 of 65

1.66

3.21

1.54e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

5 of 46

1.6

1.83

3.34e-05

GOCC:0044391

Ribosomal subunit

3 of 17

1.81

1.42

0.0012

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 7

2.02

1.1

0.0079

GOCC:0043229

Intracellular organelle

8 of 400

0.87

0.78

0.00018

GOCC:0005622

Intracellular

11 of 1532

0.42

0.35

0.0014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

8 of 70

1.62

3.03

3.98e-10

KW-0699

rRNA-binding

5 of 40

1.66

2.18

3.85e-06

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