STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (116 aa)    
Predicted Functional Partners:
ADU97094.1
KEGG: dps:DP0583 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
 
 0.991
ADU97088.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dps:DP0575 Ni/Fe-hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.970
ADU97198.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.886
ADU97090.1
KEGG: gur:Gura_1947 hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein.
 
  
 0.883
ADU97091.1
KEGG: tgr:Tgr7_1272 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
  
  
 0.861
ADU97082.1
(NiFe) hydrogenase maturation protein HypF; KEGG: aae:aq_672 transcriptional regulatory protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase.
 
   
 0.829
ADU96891.1
KEGG: nmu:Nmul_A1667 hydrogenase formation HypD protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
  
 0.784
ADU97093.1
PFAM: Methyltransferase type 11; KEGG: wch:wcw_1033 ubiquinone/menaquinone biosynthesis methyltransferase.
       0.784
ADU96889.1
KEGG: hmo:HM1_1487 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
  
 0.756
ADU97087.1
TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: dps:DP0574 Ni/Fe-hydrogenase, small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
  
 0.733
Your Current Organism:
Thermovibrio ammonificans
NCBI taxonomy Id: 648996
Other names: T. ammonificans HB-1, Thermovibrio ammonificans DSM 15698, Thermovibrio ammonificans HB-1, Thermovibrio ammonificans str. HB-1, Thermovibrio ammonificans strain HB-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.