node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFN47525.1 | SFN73576.1 | SAMN04487989_101688 | SAMN04487989_103107 | methylmalonyl-CoA epimerase. | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.990 |
SFN47525.1 | SFN73607.1 | SAMN04487989_101688 | SAMN04487989_103109 | methylmalonyl-CoA epimerase. | Heterodimeric methylmalonyl-CoA mutase small subunit. | 0.986 |
SFN47525.1 | icmF | SAMN04487989_101688 | SAMN04487989_105139 | methylmalonyl-CoA epimerase. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.876 |
SFN52204.1 | SFN73576.1 | SAMN04487989_101983 | SAMN04487989_103107 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.908 |
SFN52204.1 | SFN73607.1 | SAMN04487989_101983 | SAMN04487989_103109 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Heterodimeric methylmalonyl-CoA mutase small subunit. | 0.901 |
SFN52204.1 | SFN91137.1 | SAMN04487989_101983 | SAMN04487989_10635 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Acyl-CoA hydrolase. | 0.912 |
SFN52204.1 | SFN99288.1 | SAMN04487989_101983 | SAMN04487989_10865 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Citrate synthase; Belongs to the citrate synthase family. | 0.842 |
SFN52204.1 | icmF | SAMN04487989_101983 | SAMN04487989_105139 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.649 |
SFN52204.1 | mdh | SAMN04487989_101983 | SAMN04487989_105190 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.493 |
SFN52204.1 | pckA | SAMN04487989_101983 | SAMN04487989_101323 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.677 |
SFN52204.1 | sucC | SAMN04487989_101983 | SAMN04487989_10587 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.980 |
SFN52204.1 | sucD | SAMN04487989_101983 | SAMN04487989_102363 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.971 |
SFN73576.1 | SFN47525.1 | SAMN04487989_103107 | SAMN04487989_101688 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | methylmalonyl-CoA epimerase. | 0.990 |
SFN73576.1 | SFN52204.1 | SAMN04487989_103107 | SAMN04487989_101983 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.908 |
SFN73576.1 | SFN73607.1 | SAMN04487989_103107 | SAMN04487989_103109 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Heterodimeric methylmalonyl-CoA mutase small subunit. | 0.996 |
SFN73576.1 | SFN91137.1 | SAMN04487989_103107 | SAMN04487989_10635 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Acyl-CoA hydrolase. | 0.969 |
SFN73576.1 | SFN99288.1 | SAMN04487989_103107 | SAMN04487989_10865 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Citrate synthase; Belongs to the citrate synthase family. | 0.928 |
SFN73576.1 | icmF | SAMN04487989_103107 | SAMN04487989_105139 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.999 |
SFN73576.1 | mdh | SAMN04487989_103107 | SAMN04487989_105190 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.932 |
SFN73576.1 | pckA | SAMN04487989_103107 | SAMN04487989_101323 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.930 |