STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0016SSS sodium solute transporter superfamily; COGs: COG4146 symporter; InterPro IPR019900:IPR001734; KEGG: plu:plu1803 putative symporter YidK; PFAM: Na+/solute symporter; SPTR: Putative uncharacterized protein; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (527 aa)    
Predicted Functional Partners:
Lbys_0015
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
       0.787
Lbys_0013
5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family.
       0.772
Lbys_0018
2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel.
       0.761
Lbys_0014
5-dehydro-2-deoxygluconokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: dfe:Dfer_5700 PfkB domain protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase.
       0.760
Lbys_0019
Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
       0.760
Lbys_0017
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR010061:IPR015590; KEGG: dfe:Dfer_5699 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
       0.757
Lbys_0012
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: dfe:Dfer_5696 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; manually curated; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases.
       0.740
Lbys_1266
COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: dfe:Dfer_2903 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.630
Lbys_0010
Glycosyl hydrolase family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sli:Slin_0456 glycosyl hydrolase family 88; PFAM: glycosyl hydrolase family 88; SPTR: Glycosyl hydrolase family 88; PFAM: Glycosyl Hydrolase Family 88.
  
    0.511
Lbys_0008
KEGG: sli:Slin_1222 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.505
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.