STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0185KEGG: fjo:Fjoh_3022 hypothetical protein; SPTR: Putative uncharacterized protein. (487 aa)    
Predicted Functional Partners:
Lbys_0184
DNA topoisomerase III; COGs: COG0550 Topoisomerase IA; InterProIPR018089:IPR005738:IPR006171:IPR013497:IPR 000380:IPR006154:IPR003601:IPR003602; KEGG: fjo:Fjoh_3021 DNA topoisomerase; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase III; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid.
   
 
 0.844
Lbys_0183
KilA-N, DNA-binding domain; InterPro IPR018873; KEGG: ddf:DEFDS_0289 hypothetical protein; PFAM: KilA-N, DNA-binding domain; SPTR: Putative uncharacterized protein; PFAM: ORF6N domain.
       0.750
Lbys_0166
KEGG: fjo:Fjoh_3003 hypothetical protein; SPTR: Conserved protein found in conjugate transposon TraI.
 
      0.658
Lbys_0186
KEGG: fjo:Fjoh_3023 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.556
Lbys_2252
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.544
Lbys_0187
KEGG: bth:BT_0109 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.533
Lbys_0997
KEGG: dfe:Dfer_2374 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.502
Lbys_3479
UvrD/REP helicase; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR014016:IPR014017:IPR000212; KEGG: gfo:GFO_3376 UvrD/REP family helicase; PFAM: UvrD/REP helicase; SPTR: ATP-dependent helicase; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
  
 
 0.502
Lbys_0165
InterPro IPR012424; KEGG: fjo:Fjoh_3002 TraJ family protein conjugative transposon; PFAM: TraJ family protein conjugative transposon; SPTR: TraJ family protein conjugative transposon; PFAM: Homologues of TraJ from Bacteroides conjugative transposon; TIGRFAM: Bacteroides conjugative transposon TraJ protein.
      0.500
Lbys_0167
COGs: COG3451 Type IV secretory pathway VirB4 protein; KEGG: fjo:Fjoh_3004 type IV secretory pathway VirB4 components-like protein; SPTR: Protein found in conjugate transposon; TIGRFAM: Bacteroides conjugation system ATPase, TraG family.
    
 0.456
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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