Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0201Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR020904:IPR002198:IPR002347; KEGG: cpi:Cpin_3798 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (282 aa)    
Predicted Functional Partners:
Lbys_0192
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: cpi:Cpin_0127 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
  
 
   0.770
Lbys_2452
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002347:IPR002198; KEGG: gsu:GSU1603 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative uncharacterized protein; PFAM: short chain dehydrogenase.
  
 
   0.740
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
    
 0.690
Lbys_0200
Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: pat:Patl_3536 antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: Antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase.
 
     0.648
Lbys_0784
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198; KEGG: acd:AOLE_17445 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Possible 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: short chain dehydrogenase.
  
 
   0.519
Lbys_0202
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: dfe:Dfer_4686 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Putative oxidoreductase; PFAM: Aldo/keto reductase family.
  
    0.515
Lbys_0205
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002198:IPR002347; KEGG: cgt:cgR_0065 hypothetical protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative uncharacterized protein; PFAM: short chain dehydrogenase.
 
 
  
0.487
Lbys_1643
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347:IPR020904; KEGG: sli:Slin_3404 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase.
  
 
   0.445
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.