Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbys_0508Domain of unknown function DUF1731; COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterPro IPR013549:IPR010099; KEGG: bal:BACI_c05080 putative epimerase; PFAM: domain of unknown function DUF1731; SPTR: Putative uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777. (289 aa)    
Predicted Functional Partners:
Lbys_2113
Lipocalin family protein; COGs: COG3040 Bacterial lipocalin; InterPro IPR022272:IPR002446:IPR022271:IPR013208; KEGG: fjo:Fjoh_2134 lipocalin family protein; PFAM: Lipocalin family protein; SPTR: Outer membrane lipoprotein (Lipocalin); PFAM: Lipocalin-like domain; Belongs to the calycin superfamily. Lipocalin family.
     0.876
Lbys_0509
KEGG: sli:Slin_3048 rifampin ADP-ribosyl transferase; SPTR: Rifampin ADP-ribosyl transferase; PFAM: DNA/RNA tunnel of bacterial DNA dependent RNA polymerase.
       0.631
Lbys_0507
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734:IPR013026:IPR001440; KEGG: fba:FIC_01774 hypothetical protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Putative uncharacterized protein.
       0.613
Lbys_2139
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: fba:FIC_02393 Mn-dependent transcriptional regulator MntR; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Metal-dependent transcriptional regulator; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
   
    0.576
Lbys_0646
Zinc/iron permease; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cbh:CLC_1220 ZIP family zinc transporter; PFAM: zinc/iron permease; SPTR: Zinc transporter, ZIP family; PFAM: ZIP Zinc transporter.
  
    0.574
Lbys_2983
KEGG: dfe:Dfer_3773 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.508
Lbys_0622
COGs: COG0681 Signal peptidase I; InterPro IPR019758:IPR019759:IPR000223; KEGG: sli:Slin_0245 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
   
    0.442
Lbys_0746
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sli:Slin_0631 RNA polymerase, sigma 54 subunit, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
   
    0.415
kduI
4-deoxy-L-threo-5-hexulose uronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
   
    0.406
Lbys_3134
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
     0.405
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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