| node1 | node2 | node1 annotation | node2 annotation | score |
| Lbys_0013 | Lbys_0015 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.999 |
| Lbys_0013 | Lbys_0019 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.969 |
| Lbys_0013 | Lbys_0609 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909:IPR000683:IPR006311; KEGG: dfe:Dfer_0297 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.579 |
| Lbys_0013 | Lbys_0664 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311:IPR017909:IPR000683; KEGG: dfe:Dfer_4556 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.521 |
| Lbys_0013 | Lbys_0675 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR006311:IPR012307; KEGG: dfe:Dfer_3435 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.715 |
| Lbys_0013 | Lbys_1032 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_3436 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. | 0.521 |
| Lbys_0013 | Lbys_2995 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR006311; KEGG: rbi:RB2501_09095 putative dehydrogenase-like protein; PFAM: oxidoreductase domain protein; SPTR: Putative dehydrogenase-like protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.521 |
| Lbys_0015 | Lbys_0013 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 0.999 |
| Lbys_0015 | Lbys_0019 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.971 |
| Lbys_0015 | Lbys_0609 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909:IPR000683:IPR006311; KEGG: dfe:Dfer_0297 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.525 |
| Lbys_0015 | Lbys_0664 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311:IPR017909:IPR000683; KEGG: dfe:Dfer_4556 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.525 |
| Lbys_0015 | Lbys_0675 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR006311:IPR012307; KEGG: dfe:Dfer_3435 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.827 |
| Lbys_0015 | Lbys_1032 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_3436 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. | 0.525 |
| Lbys_0015 | Lbys_2995 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR006311; KEGG: rbi:RB2501_09095 putative dehydrogenase-like protein; PFAM: oxidoreductase domain protein; SPTR: Putative dehydrogenase-like protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.525 |
| Lbys_0019 | Lbys_0013 | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 0.969 |
| Lbys_0019 | Lbys_0015 | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.971 |
| Lbys_0019 | Lbys_0675 | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR006311:IPR012307; KEGG: dfe:Dfer_3435 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.575 |
| Lbys_0609 | Lbys_0013 | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909:IPR000683:IPR006311; KEGG: dfe:Dfer_0297 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 0.579 |
| Lbys_0609 | Lbys_0015 | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909:IPR000683:IPR006311; KEGG: dfe:Dfer_0297 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.525 |
| Lbys_0609 | Lbys_0675 | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909:IPR000683:IPR006311; KEGG: dfe:Dfer_0297 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR006311:IPR012307; KEGG: dfe:Dfer_3435 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. | 0.577 |