Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
Lbys_0675Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR006311:IPR012307; KEGG: dfe:Dfer_3435 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. (306 aa)    
Predicted Functional Partners:
Lbys_0674
Arylesterase; InterPro IPR002640; KEGG: pla:Plav_2097 arylesterase; PFAM: Arylesterase; SPTR: Serum paraoxonase/arylesterase 2; PFAM: Arylesterase.
       0.775
Lbys_0015
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
  
 0.628
Lbys_0013
5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family.
 
  
 0.623
Lbys_1767
Xylose isomerase domain-containing protein TIM barrel; COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR012307; KEGG: sli:Slin_3461 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel.
 
     0.604
Lbys_0676
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021:IPR001650:IPR014014:IPR000629:IPR 014001:IPR011545:IPR005580; KEGG: dfe:Dfer_0202 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
       0.570
Lbys_2995
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR006311; KEGG: rbi:RB2501_09095 putative dehydrogenase-like protein; PFAM: oxidoreductase domain protein; SPTR: Putative dehydrogenase-like protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
 
    0.567
Lbys_0664
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311:IPR017909:IPR000683; KEGG: dfe:Dfer_4556 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
    0.555
Lbys_0673
COGs: COG0281 Malic enzyme; InterPro IPR012188:IPR012301:IPR012302:IPR002505; KEGG: dfe:Dfer_0248 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., phosphate acetyltransferase; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
       0.503
Lbys_1032
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_3436 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
 
    0.480
Lbys_0609
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909:IPR000683:IPR006311; KEGG: dfe:Dfer_0297 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
    0.470
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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