STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0689Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: fjo:Fjoh_1987 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (212 aa)    
Predicted Functional Partners:
Lbys_1292
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467:IPR000014:IPR000700:IPR001610:I PR004358; KEGG: dfe:Dfer_5761 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; GAF domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domai [...]
 
 0.974
Lbys_0688
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR005467:IPR011110:IPR011712:IPR003594; KEGG: sli:Slin_5256 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; Two component regulator propeller; ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller.
 
 
 0.969
Lbys_0503
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR003018:IPR013767:IPR013655:IPR013656:IPR003661:I PR003594:IPR001610:IPR004358; KEGG: fba:FIC_01779 PAS/PAC domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containin [...]
 
 
 0.902
Lbys_2337
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterProIPR019734:IPR005467:IPR013026:IPR002012:IPR 001440:IPR003594; KEGG: dfe:Dfer_4503 histidine kinase; PFAM: ATP-binding region ATPase domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Tetratricopeptide repeat.
 
 0.871
Lbys_1274
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterProIPR001440:IPR011712:IPR003594:IPR019734:IPR 013026; KEGG: dfe:Dfer_0415 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.866
Lbys_3403
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterProIPR019734:IPR005467:IPR013026:IPR001440:IPR 011712:IPR003594; KEGG: phe:Phep_2111 ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; Tetratricopeptide TPR_1 repeat-containing protein; SPTR: ATP-binding region ATPase domain protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.856
Lbys_1715
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR004358:IPR005467; KEGG: gfo:GFO_2118 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Two-component sensor histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.850
Lbys_1556
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: fjo:Fjoh_4738 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.848
Lbys_2994
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterProIPR001440:IPR003594:IPR019734:IPR005467:IPR 013026; KEGG: dfe:Dfer_4503 histidine kinase; PFAM: ATP-binding region ATPase domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Tetratricopeptide repeat.
 
   0.845
Lbys_0085
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: fjo:Fjoh_1988 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.788
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (22%) [HD]