close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_076123S rRNA m(5)U-1939 methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR001566:IPR002792:IPR010280; KEGG: dfe:Dfer_1077 RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; deoxyribonuclease/rho motif-related TRAM; SPTR: Putative RNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransfera [...] (467 aa)    
Predicted Functional Partners:
Lbys_0638
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.718
Lbys_1295
KEGG: phe:Phep_0632 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: ubiE/COQ5 methyltransferase family.
   
  
 0.695
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
  
 0.548
Lbys_3143
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: sli:Slin_5890 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; SPTR: Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family.
 
  
 0.545
Lbys_2178
(LSU ribosomal protein L11P)-lysine N-methyltransferase; COGs: COG2264 Ribosomal protein L11 methylase; InterPro IPR010456; KEGG: sli:Slin_5617 ribosomal L11 methyltransferase; PFAM: ribosomal L11 methyltransferase; SPTR: Ribosomal protein L11 methyltransferase; PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase.
 
   
 0.492
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: sli:Slin_0287 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete [...]
 
    0.483
Lbys_0563
tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: vha:VIBHAR_01509 hypothetical protein; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: RNA methyltransferase TrmH family; PFAM: SpoU rRNA Methylase family.
 
  
 0.482
Lbys_0760
KEGG: dfe:Dfer_0540 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.438
Lbys_1941
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
 
  
 0.416
Lbys_0228
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: dfe:Dfer_1088 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; SPTR: Putative sun protein; PFAM: NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.413
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.