Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0764Alpha-1,2-mannosidase; COGs: COG3537 Putative alpha-1 2-mannosidase; InterPro IPR005887:IPR012939; KEGG: fjo:Fjoh_2714 putative alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; SPTR: Alpha-1,2-mannosidase; TIGRFAM: alpha-1,2-mannosidase; PFAM: Glycosyl hydrolase family 92; TIGRFAM: alpha-1,2-mannosidase, putative. (747 aa)    
Predicted Functional Partners:
Lbys_2806
COGs: COG3538 conserved hypothetical protein; InterPro IPR008313; KEGG: sli:Slin_4029 hypothetical protein; PFAM: Uncharacterised conserved protein UCP028846; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1237).
  
 0.941
Lbys_1703
Beta-N-acetylhexosaminidase; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015882:IPR015883:IPR001540; KEGG: sli:Slin_2031 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; Beta-N-acetylhexosaminidase, subunit a/b; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-hexosaminidase; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2.
 
   
 0.707
Lbys_0763
4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255:IPR001969; KEGG: sli:Slin_0323 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
       0.675
Lbys_2160
Beta-N-acetylhexosaminidase; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540:IPR015883; KEGG: cpi:Cpin_1798 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2.
 
   
 0.652
Lbys_3375
Metallophosphoesterase; InterPro IPR004843; KEGG: zpr:ZPR_2508 calcineurin-like phosphoesterase; PFAM: metallophosphoesterase; SPTR: Calcineurin-like phosphoesterase; PFAM: Calcineurin-like phosphoesterase.
 
    
 0.643
Lbys_0765
DAHP synthetase I/KDSA; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701:IPR006218:IPR020822; KEGG: dfe:Dfer_4394 DAHP synthetase I/KdsA; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SPTR: DAHP synthetase I/KDSA; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: chorismate mutase related enzymes; phospho-2-dehydro-3-deoxyheptonate aldolase.
       0.618
Lbys_0762
Peptidase S41; InterPro IPR005151; KEGG: zpr:ZPR_0307 peptidase family S41; PFAM: peptidase S41; SPTR: Putative uncharacterized protein; PFAM: Peptidase family S41.
       0.594
Lbys_2488
Coagulation factor 5/8 type domain protein; COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933:IPR000421; KEGG: zpr:ZPR_4171 putative lipoprotein; PFAM: coagulation factor 5/8 type domain protein; glycoside hydrolase family 29 (alpha-L-fucosidase); SMART: glycoside hydrolase family 29 (alpha-L-fucosidase); SPTR: Putative lipoprotein; PFAM: F5/8 type C domain; Alpha-L-fucosidase.
 
   
 0.549
Lbys_2585
Glycoside hydrolase family 29 (alpha-L-fucosidase); COGs: COG3669 Alpha-L-fucosidase; InterPro IPR016286:IPR000933; KEGG: zpr:ZPR_4172 putative exported hydrolase; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); SMART: glycoside hydrolase family 29 (alpha-L-fucosidase); SPTR: Putative exporte hydrolase; PFAM: Alpha-L-fucosidase.
 
   
 0.457
Lbys_2543
Major facilitator superfamily MFS_1; COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: fba:FIC_02123 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Probable transmembrane transporter; PFAM: Major Facilitator Superfamily.
 
     0.451
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.