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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lspASignal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (195 aa)    
Predicted Functional Partners:
Lbys_0766
Proline dehydrogenase; InterPro IPR002872; KEGG: sli:Slin_5730 proline dehydrogenase; PFAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase.
       0.794
Lbys_0768
Hypothetical protein; KEGG: dfe:Dfer_0842 chromate transporter, chromate ion transporter (CHR) family; SPTR: Putative uncharacterized protein.
       0.773
Lbys_1594
Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: sli:Slin_3124 protein of unknown function DUF164; PFAM: protein of unknown function DUF164; SPTR: Putative uncharacterized protein; PFAM: Putative zinc ribbon domain.
  
     0.623
Lbys_0765
DAHP synthetase I/KDSA; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701:IPR006218:IPR020822; KEGG: dfe:Dfer_4394 DAHP synthetase I/KdsA; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; SPTR: DAHP synthetase I/KDSA; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: chorismate mutase related enzymes; phospho-2-dehydro-3-deoxyheptonate aldolase.
  
    0.618
Lbys_2105
KEGG: dfe:Dfer_3011 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF490).
 
     0.603
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
  
 0.595
Lbys_2147
KEGG: dfe:Dfer_3634 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.588
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
   
 0.578
Lbys_1563
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
    0.564
Lbys_0769
Metallophosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: pdi:BDI_1215 calcineurin superfamily phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
       0.525
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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