Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbys_0844Cysteine desulfurase, SufS subfamily; COGs: COG0520 Selenocysteine lyase; InterPro IPR010970:IPR000192; KEGG: dfe:Dfer_5780 cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; SPTR: Cysteine desulfurase, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (406 aa)    
Predicted Functional Partners:
Lbys_0842
Iron-regulated ABC transporter ATPase subunit SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR010230:IPR003439:IPR003593; KEGG: dfe:Dfer_5778 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
  
 0.998
Lbys_0843
Iron-regulated ABC transporter permease protein SufD; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR011542:IPR000825; KEGG: sli:Slin_0174 FeS assembly protein SufD; PFAM: SufBD protein; SPTR: FeS assembly protein SufD; TIGRFAM: FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1.
 
 0.998
Lbys_1743
Iron-regulated ABC transporter membrane component SufB; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825:IPR010231; KEGG: dfe:Dfer_2575 cysteine desulfurase activator complex subunit SufB; PFAM: SufBD protein; SPTR: FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.
 
 0.994
Lbys_0846
COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: dfe:Dfer_5783 Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated domain.
 
 0.987
Lbys_1281
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982:IPR000103; KEGG: chu:CHU_1778 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
  0.905
Lbys_0847
Protein of unknown function DUF59; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: sli:Slin_0162 FeS assembly SUF system protein; PFAM: protein of unknown function DUF59; SPTR: FeS assembly SUF system protein; PFAM: Domain of unknown function DUF59; TIGRFAM: FeS assembly SUF system protein.
  
 0.743
Lbys_2866
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR020578:IPR016454; KEGG: dfe:Dfer_4416 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
  
 
0.596
msrB
methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: cts:Ctha_0501 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
       0.490
Lbys_0839
Peptidase M42 family protein; COGs: COG1363 Cellulase M and related protein; InterPro IPR008007; KEGG: dfe:Dfer_4817 peptidase M42 family protein; PFAM: peptidase M42 family protein; SPTR: Peptidase M42 family protein; PFAM: M42 glutamyl aminopeptidase.
       0.417
Lbys_0840
KEGG: sti:Sthe_3182 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.401
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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