Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Lbys_0845Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: cpi:Cpin_4763 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: O-antigen biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, U [...] (431 aa)    
Predicted Functional Partners:
Lbys_1313
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: dfe:Dfer_2895 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.675
Lbys_0051
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: dfe:Dfer_2773 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.654
Lbys_0624
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: dfe:Dfer_3415 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.638
Lbys_2475
InterPro IPR003856; KEGG: sli:Slin_4936 lipopolysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Lipopolysaccharide biosynthesis protein; PFAM: Chain length determinant protein.
  
  
 0.606
Lbys_0846
COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: dfe:Dfer_5783 Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated domain.
       0.551
Lbys_0079
COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR001962; KEGG: sli:Slin_0568 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; SPTR: Asparagine synthase (Glutamine-hydrolyzing); PFAM: Asparagine synthase.
 
    0.485
Lbys_1214
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4.
  
  
 0.465
Lbys_0847
Protein of unknown function DUF59; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: sli:Slin_0162 FeS assembly SUF system protein; PFAM: protein of unknown function DUF59; SPTR: FeS assembly SUF system protein; PFAM: Domain of unknown function DUF59; TIGRFAM: FeS assembly SUF system protein.
       0.449
mraY
phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
  
 0.447
Lbys_2453
Multi antimicrobial extrusion protein MatE; InterPro IPR002528; KEGG: dfe:Dfer_0062 polysaccharide biosynthesis protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Putative uncharacterized protein; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.438
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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