STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0944Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR012318:IPR001808:IPR000595; KEGG: fba:FIC_01586 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; SPTR: Transcriptional regulator Crp family protein; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (205 aa)    
Predicted Functional Partners:
Lbys_0945
Protein of unknown function DUF81; InterPro IPR002781; KEGG: fba:FIC_01585 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; PFAM: Sulfite exporter TauE/SafE.
 
     0.686
Lbys_0503
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR003018:IPR013767:IPR013655:IPR013656:IPR003661:I PR003594:IPR001610:IPR004358; KEGG: fba:FIC_01779 PAS/PAC domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containin [...]
 
 
 0.550
Lbys_1292
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467:IPR000014:IPR000700:IPR001610:I PR004358; KEGG: dfe:Dfer_5761 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; GAF domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domai [...]
  
 
 0.521
Lbys_0946
Transposase; InterPro IPR007069; KEGG: fba:FIC_01214 transposase; PFAM: transposase; SPTR: Transposase; PFAM: Putative transposase; Belongs to the 'phage' integrase family.
 
    0.484
Lbys_0973
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: fba:FIC_01582 metallo-beta-lactamase superfamily protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Metallo-beta-lactamase superfamily protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
 
    0.473
Lbys_1798
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: dfe:Dfer_1110 adenylate/guanylate cyclase; PFAM: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
  
 0.443
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (10%) [HD]