| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lbys_0013 | Lbys_0015 | Lbys_0013 | Lbys_0015 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.999 |
| Lbys_0013 | Lbys_0018 | Lbys_0013 | Lbys_0018 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | 0.985 |
| Lbys_0013 | Lbys_0019 | Lbys_0013 | Lbys_0019 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.969 |
| Lbys_0013 | Lbys_1027 | Lbys_0013 | Lbys_1027 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: gym:GYMC10_6003 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.584 |
| Lbys_0013 | Lbys_1032 | Lbys_0013 | Lbys_1032 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_3436 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. | 0.521 |
| Lbys_0013 | Lbys_1268 | Lbys_0013 | Lbys_1268 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR006311:IPR017909; KEGG: phe:Phep_1134 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.579 |
| Lbys_0013 | rbsK | Lbys_0013 | Lbys_0371 | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.738 |
| Lbys_0015 | Lbys_0013 | Lbys_0015 | Lbys_0013 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 0.999 |
| Lbys_0015 | Lbys_0018 | Lbys_0015 | Lbys_0018 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | 0.998 |
| Lbys_0015 | Lbys_0019 | Lbys_0015 | Lbys_0019 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.971 |
| Lbys_0015 | Lbys_1027 | Lbys_0015 | Lbys_1027 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: gym:GYMC10_6003 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.525 |
| Lbys_0015 | Lbys_1032 | Lbys_0015 | Lbys_1032 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_3436 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. | 0.525 |
| Lbys_0015 | Lbys_1268 | Lbys_0015 | Lbys_1268 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR006311:IPR017909; KEGG: phe:Phep_1134 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.580 |
| Lbys_0015 | rbsK | Lbys_0015 | Lbys_0371 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.554 |
| Lbys_0018 | Lbys_0013 | Lbys_0018 | Lbys_0013 | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | 5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: dfe:Dfer_5701 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family. | 0.985 |
| Lbys_0018 | Lbys_0015 | Lbys_0018 | Lbys_0015 | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR000399:IPR012001:IPR012000:IPR011766; KEGG: dfe:Dfer_5695 thiamine pyrophosphate protein central region; PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.998 |
| Lbys_0018 | Lbys_0019 | Lbys_0018 | Lbys_0019 | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: dfe:Dfer_5698 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. | 0.996 |
| Lbys_0018 | Lbys_1027 | Lbys_0018 | Lbys_1027 | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: gym:GYMC10_6003 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.941 |
| Lbys_0018 | Lbys_1032 | Lbys_0018 | Lbys_1032 | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_3436 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. | 0.650 |
| Lbys_0018 | Lbys_1268 | Lbys_0018 | Lbys_1268 | 2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sus:Acid_1484 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR006311:IPR017909; KEGG: phe:Phep_1134 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.944 |