STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_1185Hypothetical protein; COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: cpi:Cpin_5728 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. (356 aa)    
Predicted Functional Partners:
Lbys_1182
InterPro IPR000297; KEGG: sli:Slin_0807 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: OmpA family; PPIC-type PPIASE domain.
  
    0.617
Lbys_1184
COGs: COG0714 MoxR-like ATPase; InterPro IPR011703:IPR016366; KEGG: sli:Slin_0805 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: ATPase associated with various cellular activities AAA_3; PFAM: ATPase family associated with various cellular activities (AAA).
  
    0.612
Lbys_1183
COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297; KEGG: dfe:Dfer_2499 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PPIC-type PPIASE domain.
       0.610
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
    0.590
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.577
Lbys_1181
Agmatine deiminase; COGs: COG2957 Peptidylarginine deiminase; InterPro IPR007466; KEGG: sli:Slin_0810 agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; PRIAM: Agmatine deiminase; SPTR: Agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; Belongs to the agmatine deiminase family.
       0.448
psd
Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
   0.426
Lbys_1188
Domain of unknown function DUF1801; COGs: COG4430 conserved hypothetical protein; InterPro IPR014922; KEGG: rbi:RB2501_11317 hypothetical protein; PFAM: Domain of unknown function DUF1801; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DU1801).
       0.420
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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