node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lbys_0627 | Lbys_1214 | Lbys_0627 | Lbys_1214 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | 0.552 |
Lbys_0627 | Lbys_1563 | Lbys_0627 | Lbys_1563 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.812 |
Lbys_0627 | Lbys_2035 | Lbys_0627 | Lbys_2035 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sli:Slin_4751 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.641 |
Lbys_0627 | Lbys_3538 | Lbys_0627 | Lbys_3538 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.688 |
Lbys_0627 | murE | Lbys_0627 | Lbys_2299 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.871 |
Lbys_0627 | murF | Lbys_0627 | Lbys_2304 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.750 |
Lbys_0627 | murG | Lbys_0627 | Lbys_2036 | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.984 |
Lbys_0845 | Lbys_1214 | Lbys_0845 | Lbys_1214 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: cpi:Cpin_4763 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: O-antigen biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, U [...] | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | 0.471 |
Lbys_1214 | Lbys_0627 | Lbys_1214 | Lbys_0627 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221; KEGG: dfe:Dfer_4117 Mur ligase middle domain protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Mur ligase middle domain protein; PFAM: Mur ligase family, catalytic domain; Mur ligase middle domain. | 0.552 |
Lbys_1214 | Lbys_0845 | Lbys_1214 | Lbys_0845 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: cpi:Cpin_4763 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: O-antigen biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, U [...] | 0.471 |
Lbys_1214 | Lbys_1215 | Lbys_1214 | Lbys_1215 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | Transferase hexapeptide repeat containing protein; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: dfe:Dfer_0251 putative colanic acid biosynthesis acetyltransferase WcaF; PFAM: transferase hexapeptide repeat containing protein; SPTR: Acetyltransferase. | 0.609 |
Lbys_1214 | Lbys_1216 | Lbys_1214 | Lbys_1216 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: yli:YALI0F17644g YALI0F17644p; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase (NADP(+)); SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | 0.512 |
Lbys_1214 | Lbys_1563 | Lbys_1214 | Lbys_1563 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.852 |
Lbys_1214 | Lbys_2035 | Lbys_1214 | Lbys_2035 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sli:Slin_4751 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.519 |
Lbys_1214 | Lbys_3538 | Lbys_1214 | Lbys_3538 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.474 |
Lbys_1214 | murE | Lbys_1214 | Lbys_2299 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.598 |
Lbys_1214 | murF | Lbys_1214 | Lbys_2304 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.764 |
Lbys_1214 | murG | Lbys_1214 | Lbys_2036 | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.650 |
Lbys_1215 | Lbys_1214 | Lbys_1215 | Lbys_1214 | Transferase hexapeptide repeat containing protein; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: dfe:Dfer_0251 putative colanic acid biosynthesis acetyltransferase WcaF; PFAM: transferase hexapeptide repeat containing protein; SPTR: Acetyltransferase. | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481:IPR018480; KEGG: sli:Slin_2593 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase family 4. | 0.609 |
Lbys_1215 | Lbys_1216 | Lbys_1215 | Lbys_1216 | Transferase hexapeptide repeat containing protein; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: dfe:Dfer_0251 putative colanic acid biosynthesis acetyltransferase WcaF; PFAM: transferase hexapeptide repeat containing protein; SPTR: Acetyltransferase. | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: yli:YALI0F17644g YALI0F17644p; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase (NADP(+)); SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. | 0.774 |