node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lbys_1735 | Lbys_1738 | Lbys_1735 | Lbys_1738 | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: dfe:Dfer_4013 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | KEGG: dfe:Dfer_1527 group-specific protein; SPTR: Group-specific protein. | 0.522 |
Lbys_1735 | glyA | Lbys_1735 | Lbys_1737 | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: dfe:Dfer_4013 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.787 |
Lbys_1735 | tatC | Lbys_1735 | Lbys_1736 | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: dfe:Dfer_4013 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.773 |
Lbys_1738 | Lbys_1735 | Lbys_1738 | Lbys_1735 | KEGG: dfe:Dfer_1527 group-specific protein; SPTR: Group-specific protein. | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: dfe:Dfer_4013 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | 0.522 |
Lbys_1738 | glyA | Lbys_1738 | Lbys_1737 | KEGG: dfe:Dfer_1527 group-specific protein; SPTR: Group-specific protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.522 |
Lbys_1738 | tatC | Lbys_1738 | Lbys_1736 | KEGG: dfe:Dfer_1527 group-specific protein; SPTR: Group-specific protein. | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.522 |
glyA | Lbys_1735 | Lbys_1737 | Lbys_1735 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: dfe:Dfer_4013 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | 0.787 |
glyA | Lbys_1738 | Lbys_1737 | Lbys_1738 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | KEGG: dfe:Dfer_1527 group-specific protein; SPTR: Group-specific protein. | 0.522 |
glyA | tatC | Lbys_1737 | Lbys_1736 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.804 |
tatC | Lbys_1735 | Lbys_1736 | Lbys_1735 | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: dfe:Dfer_4013 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | 0.773 |
tatC | Lbys_1738 | Lbys_1736 | Lbys_1738 | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | KEGG: dfe:Dfer_1527 group-specific protein; SPTR: Group-specific protein. | 0.522 |
tatC | glyA | Lbys_1736 | Lbys_1737 | Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.804 |