STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_1796COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: sli:Slin_5024 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (442 aa)    
Predicted Functional Partners:
Lbys_1798
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: dfe:Dfer_1110 adenylate/guanylate cyclase; PFAM: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
 
 
 0.973
Lbys_1797
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dfe:Dfer_1111 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.957
Lbys_1292
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467:IPR000014:IPR000700:IPR001610:I PR004358; KEGG: dfe:Dfer_5761 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; GAF domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domai [...]
 
0.886
Lbys_0730
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060:IPR005467:IPR001789:IPR004358:IPR 003661:IPR003594:IPR000005; KEGG: zpr:ZPR_2934 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: DNA-binding response regulator/sensor histidine kinase; PFAM: Histidine kinase-, DNA gyr [...]
 
 
 0.830
Lbys_1866
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR000005:IPR004358:IPR018060:IPR018062:IPR005829:I PR005467; KEGG: phe:Phep_0783 ATP-binding region ATPase domain protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; [...]
  
 
0.702
Lbys_2997
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sli:Slin_3276 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.698
Lbys_0503
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR003018:IPR013767:IPR013655:IPR013656:IPR003661:I PR003594:IPR001610:IPR004358; KEGG: fba:FIC_01779 PAS/PAC domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containin [...]
 
 
 
0.695
Lbys_0269
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018062:IPR011110:IPR011123:IPR003661:IPR 003594:IPR001789:IPR000005:IPR004358:IPR018060:IPR005467; KEGG: pru:PRU_2699 sensor histidine kinase/DNA-binding response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein [...]
 
 
0.629
Lbys_0837
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060:IPR005467:IPR001789:IPR018062:IPR 004358:IPR003661:IPR003594:IPR011110:IPR011123:IPR000005; KEGG: bth:BT_3049 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; [...]
  
 
0.626
Lbys_0355
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060:IPR005467:IPR001789:IPR018062:IPR 011110:IPR011123:IPR003661:IPR003594:IPR000005:IPR004358; KEGG: bth:BT_3334 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; [...]
 
 
0.621
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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