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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
Lbys_1908COGs: COG0498 Threonine synthase; InterPro IPR000634:IPR004450:IPR001926; KEGG: dfe:Dfer_3806 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (434 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.999
Lbys_0631
COGs: COG0527 Aspartokinase; InterProIPR018042:IPR019811:IPR011147:IPR001048:IPR 002912:IPR005106:IPR001342:IPR001341; KEGG: sli:Slin_4514 aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Aspartate kinase; TIGRFAM: aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase.
 
 
 0.996
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.949
Lbys_0633
Aminotransferase class V; COGs: COG1932 Phosphoserine aminotransferase; InterPro IPR000192; KEGG: dfe:Dfer_5113 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
   
 0.937
Lbys_1176
Aminotransferase class V; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
   
 0.937
Lbys_1431
COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: amt:Amet_3510 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Threonine aldolase; PFAM: Beta-eliminating lyase.
 
 
 0.933
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.853
Lbys_2056
COGs: COG0527 Aspartokinase; InterPro IPR018042:IPR001341:IPR001048; KEGG: dfe:Dfer_3817 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family.
 
 
 0.829
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR001317:IPR011702:IPR006220:IPR006274:IPR 002474:IPR000991:IPR017926; KEGG: dfe:Dfer_4372 carbamoyl phosphate synthase small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
     
 0.801
Lbys_1906
KEGG: cpi:Cpin_6309 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3037).
       0.773
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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