STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_1917COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: phe:Phep_0639 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Propionyl-CoA carboxylase beta chain; PFAM: Carboxyl transferase domain. (513 aa)    
Predicted Functional Partners:
Lbys_1915
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 0.999
Lbys_1913
Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089; KEGG: gfo:GFO_0974 biotin carboxyl carrier protein of acyl-CoA carboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: Biotin carboxyl carrier protein of acyl-CoA carboxylase; PFAM: Biotin-requiring enzyme.
 
 0.998
Lbys_1757
methylmalonyl-CoA epimerase; InterPro IPR004360:IPR017515; KEGG: fjo:Fjoh_0659 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lactoylglutathione lyase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
 
 
 0.981
Lbys_2828
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020615:IPR020610:IPR002155:IPR020616:IPR 020617; KEGG: dfe:Dfer_3553 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.932
Lbys_1916
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR006159:IPR006099:IPR006158; KEGG: sli:Slin_6640 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
 
  
 0.927
Lbys_1690
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.917
Lbys_3134
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.917
Lbys_0017
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR010061:IPR015590; KEGG: dfe:Dfer_5699 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
   
 
 0.907
Lbys_1290
Quinone oxidoreductase, YhdH/YhfP family; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149:IPR014188; KEGG: pag:PLES_34941 putative oxidoreductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Probable oxidoreductase; TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family.
   
 
 0.905
Lbys_1914
Hypothetical protein; COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; KEGG: mkm:Mkms_3184 methylmalonyl-CoA mutase, beta subunit; SPTR: Methylmalonyl-CoA mutase, small subunit; PFAM: Methylmalonyl-CoA mutase.
 
   
 0.872
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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