STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_1937Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002347:IPR002198; KEGG: sli:Slin_0415 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (257 aa)    
Predicted Functional Partners:
Lbys_1938
Ureidoglycolate lyase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: zpr:ZPR_4369 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 0.989
Lbys_1586
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: zpr:ZPR_3768 O-methyltransferase protein; PFAM: O-methyltransferase family 3; SPTR: O-methyltransferase protein; PFAM: O-methyltransferase.
 
  
 
 0.848
Lbys_1924
InterPro IPR008000; KEGG: cpi:Cpin_1991 protein of unknown function DUF718; PFAM: protein of unknown function DUF718; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF718).
  
    0.674
Lbys_1528
Amidohydrolase 2; COGs: COG3618 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: gfo:GFO_1704 amidohydrolase family protein; PFAM: amidohydrolase 2; SPTR: Amidohydrolase family protein; PFAM: Amidohydrolase.
 
    0.587
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.524
Lbys_2499
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043; KEGG: chu:CHU_2469 [acyl-carrier-protein] S-malonyltransferase; PFAM: Acyl transferase; SPTR: [Acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.457
Lbys_1754
alpha-L-rhamnosidase; InterPro IPR008902; KEGG: pdi:BDI_1319 glycoside hydrolase family protein; PFAM: alpha-L-rhamnosidase; SPTR: Glycoside hydrolase family 78; PFAM: Bacterial alpha-L-rhamnosidase.
   
 
 0.456
Lbys_1755
alpha-L-rhamnosidase; InterPro IPR013737:IPR008902:IPR016007; KEGG: bth:BT_2524 alpha-rhamnosidase; PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain.
   
 
 0.456
Lbys_1292
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467:IPR000014:IPR000700:IPR001610:I PR004358; KEGG: dfe:Dfer_5761 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; GAF domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domai [...]
    
 
 0.415
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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