Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_1994Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002347:IPR002198; KEGG: pae:PA3128 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Probable short-chain dehydrogenase; PFAM: short chain dehydrogenase. (242 aa)    
Predicted Functional Partners:
Lbys_1993
InterPro IPR013096; KEGG: bcj:BCAM0980 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain.
 
     0.807
Lbys_1995
Ketopantoate reductase ApbA/PanE domain protein; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752; KEGG: sli:Slin_2608 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; SPTR: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase.
       0.776
Lbys_1996
COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839; KEGG: dfe:Dfer_0750 transcriptional regulator, GntR family with aminotransferase domain; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family with aminotransferase domain; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II.
       0.552
Lbys_2827
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: sli:Slin_4424 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.504
Lbys_1360
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020904:IPR002347; KEGG: dfe:Dfer_1833 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Cyclohexanol dehydrogenase; PFAM: short chain dehydrogenase.
 
    
0.426
Lbys_2138
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149:IPR002539; KEGG: maq:Maqu_2810 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; MaoC domain protein dehydratase; SPTR: Alcohol dehydrogenase, zinc-binding domain protein; PFAM: MaoC like domain; Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
  
 0.414
Lbys_2560
Ankyrin; InterPro IPR002110:IPR020683; KEGG: dfe:Dfer_1667 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
   
 0.407
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (34%) [HD]