STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Lbys_1995Ketopantoate reductase ApbA/PanE domain protein; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752; KEGG: sli:Slin_2608 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; SPTR: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase. (260 aa)    
Predicted Functional Partners:
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.931
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.931
Lbys_1994
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002347:IPR002198; KEGG: pae:PA3128 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Probable short-chain dehydrogenase; PFAM: short chain dehydrogenase.
       0.776
Lbys_1993
InterPro IPR013096; KEGG: bcj:BCAM0980 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain.
       0.773
Lbys_0114
DNA-N1-methyladenine dioxygenase; COGs: COG3145 Alkylated DNA repair protein; InterPro IPR005123; KEGG: phe:Phep_1031 2OG-Fe(II) oxygenase; PFAM: 2OG-Fe(II) oxygenase; SPTR: Alkylated DNA repair protein; PFAM: 2OG-Fe(II) oxygenase superfamily.
   
    0.761
Lbys_1996
COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839; KEGG: dfe:Dfer_0750 transcriptional regulator, GntR family with aminotransferase domain; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family with aminotransferase domain; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II.
 
     0.668
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
  
 0.428
Lbys_0123
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: cpi:Cpin_6177 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Putative AraC family transcriptional regulatory protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.426
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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