STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Lbys_2006Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR020904:IPR002347:IPR002198; KEGG: gfo:GFO_1525 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase family protein; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (230 aa)    
Predicted Functional Partners:
Lbys_1489
InterPro IPR013114; KEGG: fjo:Fjoh_1081 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase, FabA/FabZ; PFAM: FabA-like domain.
    
  0.902
lpxC
3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
    
  0.902
Lbys_1475
COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR020615:IPR018201; KEGG: fps:FP2284 3-oxoacyl-(acyl-carrier-protein) synthase I; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-(Acyl-carrier-protein) synthase I; manually curated; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
   
  0.901
Lbys_1498
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: fjo:Fjoh_1093 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; SPTR: Beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
  0.901
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
      0.900
Lbys_1508
COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR013747; KEGG: fjo:Fjoh_1102 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase III protein DarB; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal.
    
 0.663
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
   
 0.663
Lbys_2790
Beta-ketoacyl-acyl-carrier-protein synthase III; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR013751:IPR013747; KEGG: phe:Phep_0028 beta-ketoacyl-acyl-carrier-protein synthase I; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase III; SPTR: 3-oxoacyl-acyl-carrier-protein synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carri [...]
    
 0.663
Lbys_1171
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
   
  0.655
Lbys_1495
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR018201; KEGG: fjo:Fjoh_1088 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; SPTR: Beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
   
  0.655
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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