STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (344 aa)    
Predicted Functional Partners:
Lbys_1279
Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265:IPR014351; KEGG: phe:Phep_3443 hypothetical protein; PFAM: Uncharacterised protein family UPF0093; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: conserved hypothetical integral membrane protein.
 
  
 0.944
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.942
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.926
Lbys_0733
COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260:IPR018375; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; PFAM: Coproporphyrinogen III oxidase.
 
   
 0.795
Lbys_2292
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR005829:IPR001958:IPR011701; KEGG: lic:LIC12361 permease; PFAM: major facilitator superfamily MFS_1; SPTR: Tetracycline resistance protein; PFAM: Major Facilitator Superfamily; TIGRFAM: Multidrug resistance protein.
 
      0.792
Lbys_2015
KEGG: sli:Slin_1179 putative lipoprotein; SPTR: Putative lipoprotein.
       0.709
Lbys_0744
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.560
Lbys_1726
COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: sli:Slin_3227 uroporphyrinogen III synthase HEM4; PFAM: Uroporphyrinogen III synthase HEM4; SPTR: Possible uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen-III synthase HemD.
 
  
 0.479
Lbys_2013
Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583:IPR004108:IPR017932; KEGG: sli:Slin_5971 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; hydrogenase large subunit domain protein; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; manually curated; PFAM: Glutamine amidotransferases class-II.
     
 0.464
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
  
 0.423
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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