| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lbys_0863 | Lbys_1543 | Lbys_0863 | Lbys_1543 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: dfe:Dfer_5479 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.461 |
| Lbys_0863 | Lbys_2144 | Lbys_0863 | Lbys_2144 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | 0.419 |
| Lbys_1329 | Lbys_2144 | Lbys_1329 | Lbys_2144 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: sli:Slin_1750 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: O-succinylbenzoic acid--CoA ligase; PFAM: AMP-binding enzyme. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | 0.432 |
| Lbys_1502 | Lbys_2144 | Lbys_1502 | Lbys_2144 | ABC-2 type transporter; InterPro IPR013525:IPR000412; KEGG: fjo:Fjoh_1095 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter, permease component; PFAM: ABC-2 type transporter. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | 0.704 |
| Lbys_1502 | Lbys_3015 | Lbys_1502 | Lbys_3015 | ABC-2 type transporter; InterPro IPR013525:IPR000412; KEGG: fjo:Fjoh_1095 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter, permease component; PFAM: ABC-2 type transporter. | Abortive infection protein; InterPro IPR003675; KEGG: sli:Slin_2393 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein; PFAM: CAAX amino terminal protease family. | 0.524 |
| Lbys_1543 | Lbys_0863 | Lbys_1543 | Lbys_0863 | Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: dfe:Dfer_5479 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.461 |
| Lbys_1543 | Lbys_2144 | Lbys_1543 | Lbys_2144 | Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: dfe:Dfer_5479 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | 0.409 |
| Lbys_1762 | Lbys_2080 | Lbys_1762 | Lbys_2080 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: afn:Acfer_0376 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme; PFAM: AMP-binding enzyme. | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: dfe:Dfer_3249 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; manually curated; PFAM: AMP-binding enzyme. | 0.921 |
| Lbys_1762 | Lbys_2144 | Lbys_1762 | Lbys_2144 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: afn:Acfer_0376 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme; PFAM: AMP-binding enzyme. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | 0.432 |
| Lbys_2080 | Lbys_1762 | Lbys_2080 | Lbys_1762 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: dfe:Dfer_3249 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; manually curated; PFAM: AMP-binding enzyme. | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: afn:Acfer_0376 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme; PFAM: AMP-binding enzyme. | 0.921 |
| Lbys_2080 | Lbys_2144 | Lbys_2080 | Lbys_2144 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: dfe:Dfer_3249 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; manually curated; PFAM: AMP-binding enzyme. | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | 0.432 |
| Lbys_2144 | Lbys_0863 | Lbys_2144 | Lbys_0863 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.419 |
| Lbys_2144 | Lbys_1329 | Lbys_2144 | Lbys_1329 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: sli:Slin_1750 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: O-succinylbenzoic acid--CoA ligase; PFAM: AMP-binding enzyme. | 0.432 |
| Lbys_2144 | Lbys_1502 | Lbys_2144 | Lbys_1502 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | ABC-2 type transporter; InterPro IPR013525:IPR000412; KEGG: fjo:Fjoh_1095 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter, permease component; PFAM: ABC-2 type transporter. | 0.704 |
| Lbys_2144 | Lbys_1543 | Lbys_2144 | Lbys_1543 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: dfe:Dfer_5479 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.409 |
| Lbys_2144 | Lbys_1762 | Lbys_2144 | Lbys_1762 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: afn:Acfer_0376 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme; PFAM: AMP-binding enzyme. | 0.432 |
| Lbys_2144 | Lbys_2080 | Lbys_2144 | Lbys_2080 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: dfe:Dfer_3249 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; manually curated; PFAM: AMP-binding enzyme. | 0.432 |
| Lbys_2144 | Lbys_2145 | Lbys_2144 | Lbys_2145 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | Transcriptional regulator, HxlR family; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: cpi:Cpin_2871 transcriptional regulator, HxlR family; PFAM: helix-turn-helix HxlR type; SPTR: Transcriptional regulator, HxlR family; PFAM: HxlR-like helix-turn-helix. | 0.568 |
| Lbys_2144 | Lbys_2503 | Lbys_2144 | Lbys_2503 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: fps:FP0294 ABC transporter permease; PFAM: ABC-2 type transporter; SPTR: ABC family transporter permease protein; PFAM: ABC-2 type transporter. | 0.704 |
| Lbys_2144 | Lbys_3015 | Lbys_2144 | Lbys_3015 | COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fjo:Fjoh_4487 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. | Abortive infection protein; InterPro IPR003675; KEGG: sli:Slin_2393 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein; PFAM: CAAX amino terminal protease family. | 0.488 |