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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_2155RNA-metabolising metallo-beta-lactamase; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: dfe:Dfer_3744 beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain. (464 aa)    
Predicted Functional Partners:
Lbys_3187
WD40 repeat, subgroup; InterProIPR001680:IPR019782:IPR017986:IPR019775:IPR 020472:IPR019781; KEGG: chu:CHU_0759 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Putative uncharacterized protein; PFAM: WD domain, G-beta repeat.
    
 0.947
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.817
Lbys_2156
Oligoendopeptidase, M3 family; COGs: COG1164 Oligoendopeptidase F; InterPro IPR011976:IPR001567; KEGG: sli:Slin_5185 oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; SPTR: Oligoendopeptidase, M3 family; TIGRFAM: oligoendopeptidase, M3 family; PFAM: Peptidase family M3; TIGRFAM: oligoendopeptidase, M3 family.
  
    0.791
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.789
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.743
Lbys_0699
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  0.737
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.725
Lbys_0126
Metallophosphoesterase; InterPro IPR004843; KEGG: cpi:Cpin_0975 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
  
 0.724
Lbys_1144
PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR002054:IPR003141; KEGG: dfe:Dfer_5653 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; DNA polymerase X; SPTR: PHP domain protein; PFAM: PHP domain.
    
 0.692
Lbys_0561
InterPro IPR000504; KEGG: cli:Clim_2119 RNP-1 like RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain).
   
 0.657
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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