Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbys_2161COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR006282:IPR007371; KEGG: sli:Slin_2799 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; SPTR: Thiamine pyrophospokinase; TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase. (222 aa)    
Predicted Functional Partners:
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
 
  0.923
Lbys_0380
Transcriptional activator, TenA family; COGs: COG0819 Putative transcription activator; InterPro IPR004305; KEGG: cat:CA2559_10853 putative transcriptional activator (TenA family); PFAM: TENA/THI-4 domain-containing protein; SPTR: Putative transcriptional activator (TenA family); PFAM: TENA/THI-4/PQQC family.
    
 0.914
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
     
 0.907
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.905
Lbys_2088
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952:IPR006311; KEGG: fjo:Fjoh_3187 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Lbys_2160
Beta-N-acetylhexosaminidase; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540:IPR015883; KEGG: cpi:Cpin_1798 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2.
       0.773
Lbys_1211
Hypothetical protein; InterPro IPR008162; KEGG: dfe:Dfer_2826 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.624
Lbys_0054
KEGG: sli:Slin_2569 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.533
Lbys_0442
Glycosyl transferase family 39; COGs: COG5305 membrane protein; InterPro IPR003342; KEGG: sli:Slin_2543 membrane protein-like protein; PFAM: glycosyl transferase family 39; SPTR: Membrane protein-like protein; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
  
     0.513
Lbys_1706
InterPro IPR005181; KEGG: sli:Slin_5096 hypothetical protein; PFAM: protein of unknown function DUF303 acetylesterase; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF303).
  
     0.468
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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