Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Lbys_2166SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sli:Slin_6180 SNF2-related protein; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: SNF2-related protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. (962 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.855
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.832
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.829
Lbys_2252
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.822
Lbys_0699
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.811
Lbys_3187
WD40 repeat, subgroup; InterProIPR001680:IPR019782:IPR017986:IPR019775:IPR 020472:IPR019781; KEGG: chu:CHU_0759 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Putative uncharacterized protein; PFAM: WD domain, G-beta repeat.
 
 
 0.767
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.603
Lbys_2560
Ankyrin; InterPro IPR002110:IPR020683; KEGG: dfe:Dfer_1667 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
    
 0.557
Lbys_2165
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); KEGG: sli:Slin_5892 enoyl-(acyl-carrier-protein) reductase (NADH); PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: Enoyl-(Acyl-carrier-protein) reductase (NADH).
       0.528
Lbys_1113
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR011545:IPR001650:IPR018329:IPR014021:IPR 014001; KEGG: sli:Slin_5465 ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; manually curated; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
 
 
 0.524
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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