Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbys_2169COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR018322:IPR006148:IPR003737; KEGG: sli:Slin_5415 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; LmbE family protein; SPTR: Glucosamine-6-phosphate isomerase; TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase. (637 aa)    
Predicted Functional Partners:
Lbys_1408
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680:IPR003764; KEGG: dfe:Dfer_2786 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
 0.990
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: dfe:Dfer_1231 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.927
Lbys_3085
COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600:IPR005829; KEGG: sli:Slin_1583 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family.
    
 0.915
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.914
Lbys_2840
KEGG: dfe:Dfer_3304 mannose-6-phosphate isomerase type II; SPTR: Mannose-6-phosphate isomerase type II; PFAM: Mannose-6-phosphate isomerase.
     
 0.903
cutC
CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
 
   
 0.634
Lbys_2486
COGs: COG4299 conserved hypothetical protein; KEGG: fjo:Fjoh_4820 hypothetical protein; SPTR: Uncharacterized protein; PFAM: Protein of unknown function (DUF1624).
 
    0.616
Lbys_2160
Beta-N-acetylhexosaminidase; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540:IPR015883; KEGG: cpi:Cpin_1798 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2.
 
   
 0.574
Lbys_1703
Beta-N-acetylhexosaminidase; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015882:IPR015883:IPR001540; KEGG: sli:Slin_2031 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; Beta-N-acetylhexosaminidase, subunit a/b; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-hexosaminidase; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2.
 
   
 0.522
murQ
Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
 
   
 0.517
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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