STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (495 aa)    
Predicted Functional Partners:
Lbys_1564
COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR000447; KEGG: sli:Slin_6051 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
 0.998
Lbys_2962
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: lbl:LBL_2439 glycerol uptake facilitator protein; PFAM: major intrinsic protein; SPTR: Glycerol uptake facilitator protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
 0.961
plsY
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.922
Lbys_0560
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959:IPR003593; KEGG: cpi:Cpin_2822 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: ATPase central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
   
  0.848
Lbys_2560
Ankyrin; InterPro IPR002110:IPR020683; KEGG: dfe:Dfer_1667 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
   
 0.780
Lbys_2546
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
    0.725
Lbys_0027
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484:IPR001478; KEGG: fba:FIC_01278 WD40-like beta propeller; PFAM: peptidase M28; SMART: PDZ/DHR/GLGF domain protein; SPTR: WD40-like beta Propeller; PFAM: Peptidase family M28.
   
 0.703
Lbys_2644
HtrA2 peptidase; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001940:IPR001254; KEGG: dfe:Dfer_3918 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: Protease Do; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family.
   
 0.696
Lbys_3159
KEGG: dfe:Dfer_3623 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Trypsin.
   
 0.696
Lbys_3325
COGs: COG0372 Citrate synthase; InterPro IPR019810:IPR002020:IPR010953; KEGG: dfe:Dfer_0554 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; citrate synthase I (hexameric type); Belongs to the citrate synthase family.
   
 
 0.617
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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