Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Lbys_2452Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002347:IPR002198; KEGG: gsu:GSU1603 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative uncharacterized protein; PFAM: short chain dehydrogenase. (281 aa)    
Predicted Functional Partners:
Lbys_1475
COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR020615:IPR018201; KEGG: fps:FP2284 3-oxoacyl-(acyl-carrier-protein) synthase I; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-(Acyl-carrier-protein) synthase I; manually curated; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  0.916
Lbys_1498
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: fjo:Fjoh_1093 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; SPTR: Beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  0.916
lpxC
3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
  
 
 0.914
Lbys_1489
InterPro IPR013114; KEGG: fjo:Fjoh_1081 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase, FabA/FabZ; PFAM: FabA-like domain.
  
 
  0.904
Lbys_1586
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: zpr:ZPR_3768 O-methyltransferase protein; PFAM: O-methyltransferase family 3; SPTR: O-methyltransferase protein; PFAM: O-methyltransferase.
 
  
   0.879
Lbys_3074
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR002347:IPR020904; KEGG: dfe:Dfer_3961 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative oxidoreductase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.784
Lbys_2453
Multi antimicrobial extrusion protein MatE; InterPro IPR002528; KEGG: dfe:Dfer_0062 polysaccharide biosynthesis protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Putative uncharacterized protein; PFAM: Polysaccharide biosynthesis protein.
  
    0.777
Lbys_0243
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR002347; KEGG: phe:Phep_3274 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Probable dehydrogenase/reductase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.775
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene -1-carboxylic-acidsynthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
       0.774
Lbys_2368
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  0.749
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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